14-3-3 Antibody Summary
| Immunogen |
14.3.3 recombinant protein of human origin |
| Specificity |
This antibody recognizes ~26-33 kDa of human 14.3.3 beta, gamma, sigma and seta isoforms of 14.3.3. This antibody reacts with human.. The other species are not tested. |
| Isotype |
IgG1 Kappa |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
YWHAQ |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 0.01-0.1 ug/ml
- Immunoprecipitation 2-5 ug/ml
- Western Blot 1-2 ug/ml
|
Reactivity Notes
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
Sterile TBS (pH 7.2) with antibody stabilizer |
| Preservative |
No Preservative |
| Purity |
Immunogen affinity purified |
Alternate Names for 14-3-3 Antibody
Background
The 14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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