14-3-3 sigma/Stratifin [p Ser248] Antibody

Name: 14-3-3 sigma/Stratifin [p Ser248] Antibody
Brand: Novus Biologicals
SKU: NBP1-52856
Price: 329 USD
Availability: Discontinued

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Summary

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Catalog Number

NBP1-52856
Availability

Product Discontinued

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14-3-3 sigma/Stratifin [p Ser248] Antibody Summary

Immunogen	Synthetic peptides derived from Cter domain of Stratifin protein containing phosphoserine 248
Modification	p Ser248
Specificity	Antiserum reacts specifically with the human 27 kDa Stratifin pS248 protein.
Clonality	Polyclonal
Host	Rabbit
Gene	SFN
Purity	Unpurified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

ELISA 1:100-1:2000
Western Blot 1:100-1:2000

Reactivity Notes

Reacts with Human. May cross-react with Stratifin from mouse, rat and other species due to sequence identity.

Packaging, Storage & Formulations

Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer	Antiserum
Preservative	No Preservative
Concentration	LYOPH
Purity	Unpurified
Reconstitution Instructions	Reconstitute with 0.2 ml distilled water.

Alternate Names for 14-3-3 sigma/Stratifin [p Ser248] Antibody

14-3-3 protein sigma
1433 sigma
14-3-3 sigma
Epithelial cell marker protein 1
HME1
SFN
stratifin
YWHAS

Background

14-3-3 family of proteins is composed of seven isotypes, beta, gamma, zeta, epsilon, tau, eta, and sigma, that play critical roles in cell signaling events that control cell cycle progression, transcriptional alterations, and apoptosis (1-4). 14-3-3 proteins were the first signaling molecules to be identified as specific phosphoserine/threonine binding proteins (1). 14-3-3 can serve as a direct regulator of its target by altering the function of the protein (3). 14-3-3 protein targets include the signalling intermediates Raf, MEKK, PI-3 kinase and IRS-1, cell cycle proteins CDK2, Wee1, and Cdc25, and apoptosis proteins BAD and ASK-1 (3,4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol

SFN

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

14-3-3 sigma/Stratifin [p Ser248] Antibody

Species Glossary

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Product Details

Order Details

14-3-3 sigma/Stratifin [p Ser248] Antibody Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Alternate Names for 14-3-3 sigma/Stratifin [p Ser248] Antibody

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for 14-3-3 sigma/Stratifin Antibody (NBP1-52856) (0)

Reviews for 14-3-3 sigma/Stratifin Antibody (NBP1-52856) (0)

Product General Protocols

Video Protocols

FAQs for 14-3-3 sigma/Stratifin Antibody (NBP1-52856) (0)

Secondary Antibodies

Isotype Controls

Additional 14-3-3 sigma/Stratifin Products

Research Areas for 14-3-3 sigma/Stratifin Antibody (NBP1-52856)

Blogs on 14-3-3 sigma/Stratifin

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Bioinformatics