14-3-3 [p Ser185] Antibody (NB100-62101)

14-3-3 [p Ser185] Antibody (NB100-62101) (0.1 mg)

Additional Products Available View our 14-3-3 products. Call 303-730-1950 for recommended products	Ordering Information:
	Catalog Number	NB100-62101
	Size(s)	0.1 mg	Price:
	Availability
Why Choose Novus?	Bulk Quote
	View All 14-3-3 Primary Antibodies

anti-Protein HS1 antibody, anti-14-3-3 protein tau antibody, anti-protein tau antibody, anti-14-3-3 protein T-cell antibody, anti-HS1 antibody, anti-14-3-3,1C5 antibody, anti-14-3-3 protein theta antibody, anti-tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, thetapolypeptide antibody

14-3-3 [p Ser185] Antibody Summary:

Species:	Hu, Mu, Rt, Bv, Rb	Gene:	YWHAQ
Applications:	WB	Purity:	IgG purified
Clonality:	Polyclonal	Host:	Sheep
Specificity:	NB100-62101 recognizes the 14-3-3 isoforms beta and zeta which are phosphorylated at serine 185. The members of the 14-3-3 family of proteins are highly conserved and are involved in multiple signalling pathways. The phosphorylated forms of beta and zeta 14-3-3 are found endogenously in brain tissue.
Publications:

View Additional 14-3-3 Products

Peptides and Proteins	Primary Antibodies
» View All 14-3-3 Related Products

14-3-3 [p Ser185] Antibody Details:

Isotype:	IgG
Immunogen:	Synthetic peptide corresponding to 14-3-3 beta and zeta phosphorylated at serine 185.
Modification:	p Ser185

Species Reactivity:

Reacts with: Human, Bovine, Mouse, Rat, Rabbit

Applications:

Uses:	This antibody is useful for Western Blot
Dilutions:	Western Blot
Unit Size:	0.1 mg
Concentration:	Please see the vial label for concentration.

Packaging:

Storage:	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Preservative:	0.09% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: YWHAQ

Entrez:	443032 (Human)
Uniprot:	P62262 (Human)

Related Genes:

Background:

Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Images (1)


View All Images...

Be the first to review this product for a reward!

Review this product now.

14-3-3 [p Ser185] Antibody Images (1)

	WB: 14-3-3 Phosphospecific Antibody [NB100-62101] - WB with Sheep anti-14-3-3 (pSER185) antibody (AHP1049) Lane 1, 2ug recombinant 14-3-3 beta(2), 2ug recombinant 14-3-3 zeta(3), sheep brain homogenate, which contains ca. 50% of beta and zeta isoforms that are phosphorylated on Ser 185 The recombinant 14-3-3s are expressed in E.coli and are not phosphorylated.